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Inhibitory activity of cyclosporine is dependent on the activating signal(s) provided to T cells

✍ Scribed by M.anikkam. Suthanthiran


Book ID
119462385
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
283 KB
Volume
111
Category
Article
ISSN
1097-6833

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## Signal transduction through CD4 receptors: stimulatory vs. inhibitory activity is regulated by CD4 proximity to the CD31T cell receptor* The binding of antibody to the CD4 molecule inhibits mobilization of cytoplasmic free calcium ([Ca2'Ii) in response to CD3 cross-linking on resting T cells. S