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Inhibitors of poly(ADP-ribose) polymerase enhance unscheduled DNA synthesis in human peripheral lymphocytes

✍ Scribed by Masanao Miwa; Mieko Kanai; Tomoko Kondo; Hiro-o Hoshino; Kazuyuki Ishihara; Takashi Sugimura


Book ID
119407029
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
373 KB
Volume
100
Category
Article
ISSN
0006-291X

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Unscheduled synthesis of DNA and poly(AD
✍ McCurry, Lynette Salter ;Jacobson, Myron K. πŸ“‚ Article πŸ“… 1981 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 226 KB

## Abstract Unscheduled DNA synthesis has been measured in human fibroblasts under conditons of reduced rates of conversion of NAD to poly(ADP‐ribose). Cells heterozygous for the xeroderma pigmentosum genotype showed normal rates of UV induced unscheduled DNA synthesis under conditions in which the