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Inhibitors of dihydroorotate dehydrogenase

✍ Scribed by Batt, Douglas G

Book ID
121405595
Publisher
Informa plc
Year
1999
Tongue
English
Weight
126 KB
Volume
9
Category
Article
ISSN
1354-3776

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The synthesis of potentially selective i
The synthesis of potentially selective inhibitors of dihydroorotate dehydrogenase. The utilization of chemoselective Suzuki cross-coupling reactions in a parallel synthesis
✍ Amanda E Sutton; Jon Clardy πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 French βš– 101 KB

A series of potentially selective inhibitors of dihydroorotate dehydrogenase (DHODH) were synthesized via iterative, chemoselective Suzuki cross-couplings utilizing biaryl chlorides as key intermediates.