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Inhibition of β-Glucuronidase by Oral Administration of D-Glucosaccharo-1,4-Lactone

✍ Scribed by AKAMATSU, S.; KIYOMOTO, A.; HARIGAYA, S.; OHSHIMA, S.

Book ID
109616428
Publisher
Nature Publishing Group
Year
1961
Tongue
English
Weight
209 KB
Volume
191
Category
Article
ISSN
0028-0836

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D-Glucaro-1,4-lactone: Its excretion in
D-Glucaro-1,4-lactone: Its excretion in the bile and urine and effect on the biliary secretion of β-glucuronidase after oral administration in rats
✍ Andrew Macfadyen; Kang-Jey Ho 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 536 KB

This experiment was designed to test the hypothesis that orally administered D-glucaro-1,4-lactone might be excreted in the bile and thus suppress the activity of biliary 8-glucuronidase, which is believed to play a key role in the development of pigment gallstones. D-G~ucaro-1,4-lactone, 50 to 2,60