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Inhibition of urokinase-type plasminogen activator receptor induces apoptosis in melanoma cells by activation of p53

✍ Scribed by Besch, R; Berking, C; Kammerbauer, C; Degitz, K


Book ID
110017358
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
374 KB
Volume
14
Category
Article
ISSN
1350-9047

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## Abstract It has been admitted that urokinase‐type plasminogen activator receptor (u‐PAR) is overexpressed in many human malignant tumors including oral squamous cell carcinoma (OSCC) and plays an important role in a variety of cancer key cellular events as a versatile signaling orchestrator. In