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Inhibition of tumorigenicity by the 5′-untranslated RNA of the human c-myc P0 transcript

✍ Scribed by Scott W Blume; Donald M Miller; Vincenzo Guarcello; Kedar Shrestha; Zheng Meng; Richard C Snyder; William E Grizzle; J.Michael Ruppert; G.Larry Gartland; Cecil R Stockard; David E Jones Jr.; Peter D Emanuel


Book ID
117099873
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
836 KB
Volume
288
Category
Article
ISSN
0014-4827

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The 5′-untranslated RNA of the human dhf
✍ Scott W. Blume; Zheng Meng; Kedar Shrestha; Richard C. Snyder; Peter D. Emanuel 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 356 KB

## Abstract The human dhfr minor transcript is distinguished from the predominant dhfr mRNA by an ∼400 nucleotide extension of the 5′‐untranslated region, which corresponds to the major (core) promoter DNA (its template). Based on its unusual sequence composition, we hypothesized that the minor tra