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6 Rna polymerase III transcription and cancer — the opposing effects of RB, p53 and c-Myc

✍ Scribed by R.J. White

Book ID: 118620183
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 216 KB
Volume: 1
Category: Article
ISSN: 1359-6349
DOI: 10.1016/s1359-6349(03)90040-1

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## Abstract We have investigated the role of phosphorylation by vertebrate protein kinase CK2 on the activity of the General Transcription Factors TFIIA, TFIIE, TFIIF, and RNAPII. The largest subunits of TFIIA, TFIIE, and TFIIF were phosphorylated by CK2 holoenzyme. Also, RNA polymerase II was phos