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Inhibition of thymocyte negative selection by T cell receptor antagonist peptides

✍ Scribed by Owen Williams; Yujiro Tanaka; Mark Bix; Marianna Murdjeva; Dan R. Littman; Dimitris Kioussis


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
826 KB
Volume
26
Category
Article
ISSN
0014-2980

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## Peptide antagonists that promote positive selection are inefficient at T cell activation and thymocyte deletion* We set out to determine whether thymocytes from Tcell receptor (TCR) transgenic animals specific for a class I-restricted determinant from ovalbumin (OVA) showed the same fine specif