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Inhibition of the Vitamin B12Binding Capacity of Proteins by the Hydrolysis Product of Cyclophosphamide

โœ Scribed by Fenrych, Wladyslaw ;Szczodrowska, Enid ;Ignatowicz, Ewa


Book ID
114801950
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
247 KB
Volume
72
Category
Article
ISSN
0901-9928

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Under conditions of vitamin B12 deficiency the marine phytoplankton Thalassiosira pseudonana secretes into the growth medium a protein (Gm protein) that binds B12 specifically with an affinity constant of 2 x 10(11) M(-1). When Gm protein was used as a B12-specific binder in radioassays for the dire