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Inhibition of the RNase H activity of HIV reverse transcriptase by azidothymidylate

✍ Scribed by Tan, Cheng Keat; Rigal, Civil; Mian, A. Mohsin; So, Antero G.; Downey, Kathleen M.

Book ID
126984909
Publisher
American Chemical Society
Year
1991
Tongue
English
Weight
609 KB
Volume
30
Category
Article
ISSN
0006-2960

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Differential inhibition of DNA polymeras
Differential inhibition of DNA polymerase and RNase H activities of the reverse transcriptase by phosphonoformate
✍ Miriam Margalith; Haya Falk; Amos Panet πŸ“‚ Article πŸ“… 1982 πŸ› Springer 🌐 English βš– 439 KB

Three potential inhibitors of reverse transcriptase activities, phosphonoformate (PF), phosphonoacetate (PAA), and ethyl-diethyl phosphonoformate (Et-PF), were compared in this study. Only PF was found to inhibit the DNA polymerase activity of the purified reverse transcriptase of Moloney murine leu