RNase inhibition of reverse transcriptase activity in human milk
โ Scribed by McCORMICK, J. JUSTIN; LARSON, LENORA J.; RICH, MARVIN A.
- Book ID
- 109693198
- Publisher
- Nature Publishing Group
- Year
- 1974
- Tongue
- English
- Weight
- 442 KB
- Volume
- 251
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/251737a0
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๐ SIMILAR VOLUMES
Three potential inhibitors of reverse transcriptase activities, phosphonoformate (PF), phosphonoacetate (PAA), and ethyl-diethyl phosphonoformate (Et-PF), were compared in this study. Only PF was found to inhibit the DNA polymerase activity of the purified reverse transcriptase of Moloney murine leu
NT cells to measure simultaneously the promoter activities as well as transfection efficiency. The promoter activities and transfection efficiency were successfully determined by measuring the activities of P. pyralis and R. reniformis luciferases, respectively, using the dual-luciferase reporter as