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Inhibition of the ribosomal peptidyl transferase reaction by the mycarose moiety of the antibiotics carbomycin, spiramycin and tylosin

โœ Scribed by Susan M Poulsen; Christine Kofoed; Birte Vester


Book ID
115630654
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
278 KB
Volume
304
Category
Article
ISSN
0022-2836

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Aldol condensation reactions of tricarbo
โœ Michel Franck-Neumann; Philippe Geoffroy; Fabien Gumery ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 183 KB

Tricarbonyliron complexes of ฮฑ-methoxyheptadienone 3 and octadienone 8 were reacted as silyl enol ethers with protected ฮฒ-hydroxypropanal and TiCl 4 , to give the syn-syn aldol condensation products 4 and 11 as major, isolated diastereomers (61 and 45%). Products 4 and 11 were converted into key int