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Transition State Chirality and Role of the Vicinal Hydroxyl in the Ribosomal Peptidyl Transferase Reaction †

✍ Scribed by Huang, Kevin S.; Carrasco, Nicolas; Pfund, Emmanuel; Strobel, Scott A.


Book ID
126929909
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
523 KB
Volume
47
Category
Article
ISSN
0006-2960

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## Abstract Rate coefficients for the reaction of the hydroxyl radical with CH~3~OCH~2~F (HFE‐161) were computed using transition state theory coupled with ab initio methods, viz., MP2, G3MP2, and G3B3 theories in the temperature range of 200–400 K. Structures of the reactants and transition states