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Inhibition of the proliferation of acquired aromatase inhibitor-resistant breast cancer cells by histone deacetylase inhibitor LBH589 (panobinostat)

✍ Scribed by Makoto Kubo, Noriko Kanaya, Karineh Petrossian, Jingjing Ye, Charles Warden, Zheng Liu, Reiki Nishimura, Tomofumi Osako, Masayuki Okido, Kazuo Shimada, Masato Takahashi, Peiguo Chu, Yate-Ching Yuan, Shiuan Chen


Book ID
118796817
Publisher
Springer US
Year
2012
Tongue
English
Weight
900 KB
Volume
137
Category
Article
ISSN
0167-6806

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## Abstract While the apoptosis‐inducing ligand Apo2L/TRAIL is a promising new agent for the treatment of cancer, the sensitivity of cancer cells for induction of apoptosis by Apo2L/TRAIL varies considerably. Identification of agents that can be used in combination with Apo2L/TRAIL to enhance apopt