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Inactivation of NF-κB by proteasome inhibition contributes to increased apoptosis induced by histone deacetylase inhibitors in human breast cancer cells

✍ Scribed by Josep Domingo-Domènech; Raffaella Pippa; Marian Tápia; Pere Gascón; Oriol Bachs; Marta Bosch


Publisher
Springer US
Year
2007
Tongue
English
Weight
441 KB
Volume
112
Category
Article
ISSN
0167-6806

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## Abstract Breast cancer remains the major cause of cancer‐related deaths in women world‐wide. The heterogeneity of breast cancer has further complicated the progress of target‐based therapies. Triple negative breast cancers, lacking estrogen receptor, progesterone receptor and the Her‐2/neu (ErbB