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Inhibition of the phosphatidylinositol-3 kinase/Akt promotes G1 cell cycle arrest and apoptosis in Hodgkin lymphoma

✍ Scribed by Georgios V. Georgakis; Yang Li; Georgios Z. Rassidakis; L. Jeffrey Medeiros; Gordon B. Mills; Anas Younes

Book ID: 108673557
Publisher: John Wiley and Sons
Year: 2005
Tongue: English
Weight: 409 KB
Volume: 0
Category: Article
ISSN: 0007-1048
DOI: 10.1111/j.1365-2141.2005.05881.x

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## Abstract ## Background The prostate androgen‐regulated (PAR) gene is ubiquitously overexpressed in prostate cancer (PCa) cells and is involved in proliferation of PCa. However, the mechanism by which the modulation of PAR gene expression elicits its biological effects on PCa cells is not well d