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Inhibition of the Activity of Src and Abl Tyrosine Protein Kinases by the Binding of the Wiskott−Aldrich Syndrome Protein †

✍ Scribed by Schulte, Roberta J.; Sefton, Bartholomew M.


Book ID
126092338
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
145 KB
Volume
42
Category
Article
ISSN
0006-2960

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Characterization of the Wiskott-Aldrich
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Wiskott-Aldrich syndrome is an X-linked disorder characterized by thrombocytopenia, eczema and immunodeficiency. The Wiskott-Aldrich syndrome protein and the gene that encodes it have been identified by positional cloning and the protein has been shown to contain a pleckstrin-homology domain, a GTPa