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Mutations of the Wiskott–Aldrich Syndrome Protein affect protein expression and dictate the clinical phenotypes
✍ Scribed by Hans D. Ochs
- Book ID
- 107572415
- Publisher
- Springer-Verlag
- Year
- 2008
- Tongue
- English
- Weight
- 159 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0257-277X
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Wiskott-Aldrich syndrome is an X-linked disorder characterized by thrombocytopenia, eczema and immunodeficiency. The Wiskott-Aldrich syndrome protein and the gene that encodes it have been identified by positional cloning and the protein has been shown to contain a pleckstrin-homology domain, a GTPa
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