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Inhibition of T cell responses by activated CD8+ T cells is mediated by IFN-γ and is defective in chronic progressive multiple sclerosis

✍ Scribed by K.E. Balashov; S.J. Khoury; H.L. Weiner


Book ID
119108892
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
148 KB
Volume
54
Category
Article
ISSN
0165-5728

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## Abstract We were the first to demonstrate that combined immunotherapy with GM‐CSF producing GL261 cells and recombinant IFNγ of preestablished GL261 gliomas could cure 90% of immunized mice. To extend these findings and to uncover the underlying mechanisms, the ensuing experiments were undertake