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Regression of engineered myeloma cells secreting interferon-γ-inducing factor is mediated by both CD4+/CD8+ T and natural killer cells

✍ Scribed by Jim Xiang; Zhuang Chen; Hui Huang; Terence Moyana

Book ID
114119013
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
117 KB
Volume
25
Category
Article
ISSN
0145-2126

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## Abstract We were the first to demonstrate that combined immunotherapy with GM‐CSF producing GL261 cells and recombinant IFNγ of preestablished GL261 gliomas could cure 90% of immunized mice. To extend these findings and to uncover the underlying mechanisms, the ensuing experiments were undertake