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Inhibition of sustained hypoxic vasoconstriction by Y-27632 in isolated intrapulmonary arteries and perfused lung of the rat

✍ Scribed by Tom P Robertson; Michelle Dipp; Jeremy P T Ward; Phil I Aaronson; A Mark Evans


Book ID
110005215
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
132 KB
Volume
131
Category
Article
ISSN
0007-1188

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In the rat pulmonary vasculature perfused with blood in situ vasoconstriction induced by hypoxia was reversed by isoprenaline (doses greater than 1 ng) and adrenaline (doses greater than 30 ng) and exacerbated by phenylephrine but not UK 14304. Doses of adrenaline less than 30 ng had no effect, exce