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Inhibition of steroid sulphatase activity by steroidal methylthiophosphonates: Potential therapeutic agents in breast cancer

โœ Scribed by Purohit, A.; Howarth, N.M.; Potter, B.V.L.; Reed, M.J.


Book ID
122639985
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
502 KB
Volume
48
Category
Article
ISSN
0960-0760

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Oestrogen sulphatase activity in hormone
โœ A. Purohit; M. J. Reed ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 550 KB

Oestrogen sulphatase may play an important role in providing intracellular oestrogens from E,S for the growth and maintenance of breast tumours. In this study, we characterized oestrogen sulphatase in the hormone-dependent (ER/PR+) MCFJ and in the hormone-independent (ER/PR-) MDA-MB-23 I breast-canc