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Measurement of oestrone sulphatase activity in white blood cells to monitor in vivo inhibition of steroid sulphatase activity by oestrone-3-O-sulphamate

✍ Scribed by A. Purohit; V.A. Froome; D.Y. Wang; B.V.L. Potter; M.J. Reed


Book ID
117668826
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
629 KB
Volume
62
Category
Article
ISSN
0960-0760

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In vivo inhibition of oestrone sulphatas
✍ A. Purohit; G. J. Williams; C. J. Roberts; B. V. L. Potter; M. J. Reed 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 661 KB

## Abstract Many tumours in endocrine‐sensitive tissues, such as the breast and endometrium, are hormone‐dependent and the hydrolysis of oestrone sulphate (EIS) to oestrone by oestrone sulphatase (EI‐STS) is a major source of oestrogen in such tumours. Oestrone‐3‐O‐sulphamate (EMATE) has been shown