In vivo inhibition of oestrone sulphatas
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A. Purohit; G. J. Williams; C. J. Roberts; B. V. L. Potter; M. J. Reed
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Article
📅
1995
🏛
John Wiley and Sons
🌐
French
⚖ 661 KB
## Abstract Many tumours in endocrine‐sensitive tissues, such as the breast and endometrium, are hormone‐dependent and the hydrolysis of oestrone sulphate (EIS) to oestrone by oestrone sulphatase (EI‐STS) is a major source of oestrogen in such tumours. Oestrone‐3‐O‐sulphamate (EMATE) has been shown