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Inhibition of SSAO by MDL-72974, a selective MAO-B inhibitor

โœ Scribed by Zuo, D.M.; Yu, P.H.


Book ID
122782100
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
114 KB
Volume
21
Category
Article
ISSN
0197-0186

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MDL72974 is a member of a series of MAO-B inhibitors to be used as potential therapeutic agents in the treatment of Parkinson's and Alzheimer's diseases. However, we have recently observed a reduction in the density of tyrosine hydroxylase (TH)-positive neurons in the substantia nigra of mice treate