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Selective inhibition of MAO-A but not MAO-B activity increases rat pineal melatonin

✍ Scribed by G. F. Oxenkrug; R. McCauley; I. M. McIntyre; C. Filipowicz


Book ID
105135468
Publisher
Springer
Year
1985
Tongue
English
Weight
278 KB
Volume
61
Category
Article
ISSN
1435-1463

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Ontogenetic effects of MAO-A inhibition
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Inhibitors of monoamine oxidase A (MAO-A) but not MAO-B stimulate the activity of pineal serotonin N-acetyltransferase (AANAT) in the adult rat pineal leading to increased formation of N-acetyl serotonin (NAS) and melatonin (MEL). The pineal gland of the neonatal rat has AANAT activity, but the seco