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Inhibition of sphingosine kinase-2 ablates androgen resistant prostate cancer proliferation and survival

โœ Scribed by Gestaut, Matthew M.; Antoon, James W.; Burow, Matthew E.; Beckman, Barbara S.

Book ID
122068842
Publisher
Elsevier
Year
2014
Tongue
English
Weight
229 KB
Volume
66
Category
Article
ISSN
1734-1140

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## Abstract It has recently been shown that docetaxel chemotherapy is effective in prolonging life in patients with prostate cancer (PCa). We have investigated potential ways of increasing the effectiveness of chemotherapy in this disease. We have previously reported that sphingosine kinase 1 (SphK