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1075 Sphingosine kinase 1 inhibition sensitizes hormone-resistant prostate and breast cancer cells to docetaxel

โœ Scribed by D. Pshezhetskiy; L. Sauer; J. Nunes; V. Salunkhe; T. Kohama; O. Cuvillier; J. Waxman


Book ID
119600129
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
48 KB
Volume
7
Category
Article
ISSN
1359-6349

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Sphingosine kinase 1 inhibition sensitiz
โœ Lysann Sauer; Joao Nunes; Vishal Salunkhe; Lenka Skalska; Takafumi Kohama; Olivi ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 404 KB

## Abstract It has recently been shown that docetaxel chemotherapy is effective in prolonging life in patients with prostate cancer (PCa). We have investigated potential ways of increasing the effectiveness of chemotherapy in this disease. We have previously reported that sphingosine kinase 1 (SphK