## Abstract Sera from rats bearing transplanted aminoazo‐dye‐induced hepatomas inhibited the cytotoxicity of lymph‐node cells from tumour‐immune rats for plated hepatoma cells, when the sera were incubated with the effector cells, rather than target cells. In contrast, sera from hepatoma‐immune rat
Inhibition of rat lymph node cell cytotoxicity by hepatoma-associated embryonic antigen
✍ Scribed by REES, R. C.; PRICE, M. R.; BALDWIN, R. W.; SHAH, L. P.
- Book ID
- 109693874
- Publisher
- Nature Publishing Group
- Year
- 1974
- Tongue
- English
- Weight
- 323 KB
- Volume
- 252
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/252751a0
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## Abstract Serum from hepatoma‐bearing rats has been shown to abrogate the cytotoxicity of immune lymph‐node cells when added to the target cells (blocking) or the effector cells (inhibition). Neutralization of these in vitro blocking and inhibitory reactions by sera containing antibody to tumour
## Abstract Cellular and humoral immune reactions against tumour‐specific antigens on aminoazo‐dye‐induced rat hepatomas were demonstrated __in vitro__ by the colony inhibition technique. Lymph‐node cells from syngeneic rats immunized against individual hepatomas inhibited colony formation by cells
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