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Inhibition of purine nucleoside phosphorylase activity and of T-cell function with allopurinol-riboside

✍ Scribed by Y. Nishida; N. Kamatani; K. Tanimoto; I. Akaoka


Book ID
105418371
Publisher
SP Birkhäuser Verlag Basel
Year
1979
Tongue
English
Weight
274 KB
Volume
9
Category
Article
ISSN
1420-908X

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Incorporation of purine nucleosides in c
✍ Wylie G. Burke; Shi-Han Chen; C. Ronald Scott; Arthur J. Ammann Jr. 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 English ⚖ 396 KB

## Abstract Cultured skin fibroblasts from a patient with T‐cell immune deficiency and an absence of purine nucleoside phosphorylase activity in red cells were assayed for their capacity to metabolize inosine and guanosine. The cultured fibroblasts were lacking activity of nucleoside phosphorylase