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Inhibition of protein synthesis in nontolerant and thermotolerant CHO cells

✍ Scribed by R.A. Levine; W.C. Dewey

Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
133 KB
Volume
19
Category
Article
ISSN
0360-3016

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## Abstract The perception of environmental stress in animal cells engineered to produce heterologous protein leads to the induction of stress signaling pathways and ultimately apoptosis and cell death. Protein synthesis is regulated in response to various environmental stresses by phosphorylation