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Inhibition of Proteasome Function Prevents Thymocyte Apoptosis: Involvement of Ornithine Decarboxylase

โœ Scribed by Emanuela Grassilli; Francesca Benatti; Paola Dansi; Anna Maria Giammarioli; Walter Malorni; Claudio Franceschi; Maria Alfonsina Desiderio


Book ID
115582664
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
326 KB
Volume
250
Category
Article
ISSN
0006-291X

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Inhibition of proteasome function induce
โœ Xiao Ming Fan; Benjamin Chun Yu Wong; Wei Ping Wang; Xin Min Zhou; Chi Hin Cho; ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 348 KB

The ubiquitin-proteasome pathway plays a critical role in the degradation of cellular proteins and cell cycle control. Dysregulating the degradation of such proteins should have profound effects on tumor growth and causes cells to undergo apoptosis. The aims of this study are to evaluate the ubiquit