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Inhibition of polo-like kinase 1 by antisense oligonucleotides and RNA interference


Book ID
117659821
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
150 KB
Volume
38
Category
Article
ISSN
0959-8049

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## Abstract Members of the polo‐like kinases (Plk1, Plk2, Plk3 and Plk4) are involved in the regulation of various stages of the cell cycle and have been implicated in cancer progression. Unlike its other family members, the expression of Plk3 remains steady during cell cycle progression, suggestin