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Inhibition of platelet-derived growth factor-induced mitogenesis by phosphodiesterase 3 inhibitors: Role of protein kinase a in vascular smooth muscle cell mitogenesis

✍ Scribed by Michael T Osinski; Karsten Schrör


Book ID
113992312
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
609 KB
Volume
60
Category
Article
ISSN
0006-2952

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Structural changes within the blood vessel wall such as hyperplasia and hypertrophy of vascular smooth muscle cells are important factors in the pathogenesis of hypertension. Humoral growth factors such as angiotensin II (AII) and platelet-derived growth factor BB (PDGF-BB) may participate in the re