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Inhibition of phospholipase cδ by hexadecylphosphorylcholine and lysophospholipids with antitumor activity

✍ Scribed by Tadeusz Pawelczyk; John M. Lowenstein

Book ID
115783193
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
616 KB
Volume
45
Category
Article
ISSN
0006-2952

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Inhibition of phospholipase C activity by auriculatin and 8-prenylluteone isolated from Erythrina senegalensis
✍ Won Keun Oh; Hyun Sun Lee; Bo Yeon Kim; Hye Kyung Chang; Yong Hae Kim; Jean Wand 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 121 KB

Auriculatin and 8-prenylluteone were isolated from Erythrina senegalensis (Leguminosae) as inhibitors of phospholipase C (PLC) and phosphoinositides (PI)-turnover in PLC-␥1 overexpressing NIH3T3 fibroblasts (NIH3T3␥1). Auriculatin (1) and 8-prenylluteone (2) showed inhibitory activity with an IC 50