Antitumor effect of neocarzinostatin con
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Eigo Otsuji; Toshiharu Yamaguchi; Yoshihiro Yata; Hiroshi Nishi; Kazuma Okamoto;
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Article
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1994
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John Wiley and Sons
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English
β 495 KB
The anticancer agent neocarzinostatin (NCS) was bound covalently to human/mouse chimeric Fab fragments of the monoclonal antibody A7 to form the conjugate chA7Fab-NCS. The antitumor effect of chA7Fab-NCS was tested by measuring the inhibition of 3H-thymidine incorporation into human pancreatic carci