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Inhibition of NADPH oxidase 4 activates apoptosis via the AKT/apoptosis signal-regulating kinase 1 pathway in pancreatic cancer PANC-1 cells

โœ Scribed by Mochizuki, T; Furuta, S; Mitsushita, J; Shang, W H; Ito, M; Yokoo, Y; Yamaura, M; Ishizone, S; Nakayama, J; Konagai, A


Book ID
110070427
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
289 KB
Volume
25
Category
Article
ISSN
0950-9232

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## Abstract Notch signaling is involved in a variety of cellular processes, such as cell fate specification, differentiation, proliferation, and survival. Notchโ€1 overโ€expression has been reported in prostate cancer metastases. Likewise, Notch ligand Jaggedโ€1 was found to be overโ€expressed in metas