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Inhibition of mTOR by rapamycin in the amygdala or hippocampus impairs formation and reconsolidation of inhibitory avoidance memory

✍ Scribed by Paulo F.C. Jobim; Thiago R. Pedroso; Raissa R. Christoff; Aline Werenicz; Natasha Maurmann; Gustavo K. Reolon; Rafael Roesler


Book ID
116792065
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
474 KB
Volume
97
Category
Article
ISSN
1074-7427

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## Abstract Using two different mRNA synthesis inhibitors, we show that blockade of hippocampal gene expression during restricted posttraining or postretrieval time windows hinders retention of long‐term spatial memory for the Morris water maze task, without affecting short‐term memory, nonspatial