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Inhibition of mixed function oxidases in rat liver by trans- and cis-1,2-dichloroethylene

✍ Scribed by K.J Freundt; J Macholz


Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
478 KB
Volume
10
Category
Article
ISSN
0300-483X

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The inhibition by colchicine of the init
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## Abstract Colchicine inhibited the initiation of DNA synthesis by hepatocytes in vivo and by WI‐38 and C3H10T 1/2 cells in vitro. All three cell types were most sensitive to colchicine when it was administered at the time of, or shortly after, proliferative activation (by partial hepatectomy or m