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Inhibition of microsome-mediated binding of aflatoxin B1 to DNA by glutathione S-transferase

✍ Scribed by Lotlikar, Prabhaker D.; Insetta, Susan M.; Lyons, Paula R.; Jhee, Eun-Chung


Book ID
123314000
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
539 KB
Volume
9
Category
Article
ISSN
0304-3835

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Methylenedioxyphenyl substituted compoun
✍ Hanumantharao G. Raj; Sangita Gupta; Ashok K. Prasad; Per M. Boll; Jesper Wengel πŸ“‚ Article πŸ“… 1995 πŸ› Elsevier Science 🌐 English βš– 279 KB

Several compounds from Piper species bearing methylenedioxyphenyi moieties are reported for the first time to effectively inhibit the rat liver microsome-mediated afiatoxin B~-DNA binding in vitro. From the preliminary results obtained, a structure-activity relationship is proposed. Attatoxin B 1 (