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Inhibition of membrane-bound succinate dehydrogenase by disulfiram

✍ Scribed by David Jay

Publisher
Springer US
Year
1991
Tongue
English
Weight
442 KB
Volume
23
Category
Article
ISSN
0145-479X

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In vitro kinetics of the rat brain succi
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✍ V. Lokanatha; P. Sailaja; W. Rajendra πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 82 KB πŸ‘ 2 views

Brain succinate dehydrogenase (SDH) activity was inhibited by in vitro hexachlorophene (HCP) with a half inhibitory concentration (IC 50 ) of 0.65 ‫‬ 10 ‫3‬ M. The HCP exerted noncompetitive inhibition at 0.5 mM (Ο½IC 50 ), uncompetitive inhibition at 0.65 mM (IC 50 ), and mixed-type inhibition at 0.