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Inhibition of melanoma brain metastasis by targeting melanotransferrin at the cell surface

✍ Scribed by Yannève Rolland; Michel Demeule; Laurence Fenart; Richard Béliveau

Book ID
118074648
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
439 KB
Volume
22
Category
Article
ISSN
1755-1471

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We have studied the experimental metastasis of H-2+ and H-2-melanoma sublines in H-2b/b and H-Zdb hosts by enumerating pulmonary colonies 20-50 days after i.v. inoculation of tumor cells. In H-2b'b hosts, the H-2+ "616-S" cells gave rise to a moderate number of metastatic colonies (mean: 6.3 f 6). T