𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Inhibition of Matrix Metalloproteinases: An examination of the S1′ pocket

✍ Scribed by Andrew Miller; Marion Askew; R.Paul Beckett; Claire L. Bellamy; Elisabeth A. Bone; Rachael E. Coates; Alan H. Davidson; Alan H. Drummond; Philip Huxley; Fionna M. Martin; Lydia Saroglou; Alison J. Thompson; Sonja E. van Dijk; Mark Whittaker

Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
290 KB
Volume
7
Category
Article
ISSN
0960-894X

No coin nor oath required. For personal study only.

✦ Synopsis

Peptidomimetic carboxylate-and hydroxamate-based inhibitors of matrix metalloproteinases containing extended PI' groups have been prepared. Potent inhibition and good selectivity for MMP-2 has been observed for the compounds produced.

📜 SIMILAR VOLUMES

Low molecular weight inhibitors of matri
Low molecular weight inhibitors of matrix metalloproteinases can enhance the expression of matrix metalloproteinase-2 (gelatinase A) without inhibiting its activation
✍ Erika H. M. Kerkvliet; Ineke D. C. Jansen; Ton A. M. Schoenmaker; Andy J. P. Doc 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 180 KB

## Background: In the current study, the authors investigated the effects of synthetic low molecular weight inhibitors of matrix metalloproteinases (mmps) on the expression and activation of mmp-2 in a three-dimensional tissue system. ## Methods: Rabbit periosteal explants were cultured with or w