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Inhibition of matrix metalloproteinase activity reduces collagen lattice contraction by Dupuytren's fibroblasts

✍ Scribed by W. Townley; A.D. Cambrey; P.T. Khaw; A.O. Grobbelaar

Book ID
119200841
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
42 KB
Volume
59
Category
Article
ISSN
1878-0539

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## Abstract Fibroblast‐populated collagen lattices (FPCL), prepared in petri dishes with serum‐containing culture medium and incubated at 37Β°C, undergo progressive and symmetric contraction (reduction in size) over a period of days. The in vitro contraction process requires viable cells with intact