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Inhibition of LTB4 monocyte production by interleukin-1 receptor antagonist (IL-1RA)

✍ Scribed by Conti, Pio; Panara, Maria R.; Barbacane, Renato C.; Reale, Marcella; Bongrazio, Mauro; Theoharides, Theoharis C.

Book ID: 123127410
Publisher: Elsevier Science
Year: 1991
Tongue: English
Weight: 180 KB
Volume: 3
Category: Article
ISSN: 1043-4666
DOI: 10.1016/1043-4666(91)90348-H

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## Abstract The pro‐inflammatory cytokine interleukin‐1 (IL‐1), contributes to neuronal inflammation and cell death induced by ischemia, excitotoxicity, or trauma, while administration of IL‐1 receptor antagonist (IL‐1ra) reduces neuronal injury. The aim of the present study was to test the hypothe