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Imbalance Production between Interleukin-1β (IL-1β) and IL-1 Receptor Antagonist (IL-1Ra) in Bronchial Asthma

✍ Scribed by Xiao-Quan Mao; Mitsuru Kawai; Tetsuji Yamashita; Tadao Enomoto; Yasuhiro Dake; Sei Sasaki; Yoko Kataoka; Takayuki Fukuzumi; Kaoru Endo; Hozumi Sano; Toshiyuki Aoki; Fumihiko Kurimoto; Chaker N. Adra; Taro Shirakawa; Julian M. Hopkin

Book ID
115586596
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
61 KB
Volume
276
Category
Article
ISSN
0006-291X

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## Abstract ## BACKGROUND The principal components of the interleukin‐1 (IL‐1) family are two secreted factors (IL‐1α and IL‐1β), two transmembrane receptors (IL‐1RI [biologically active] and IL‐1RII [inert receptor]), and a natural antagonist receptor of IL‐1 function (IL‐1Ra). Changes in the exp