𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Inhibition of isolation-induced aggressive behavior with GABA transaminase inhibitors

✍ Scribed by John P. DaVanzo; M. Sydow

Book ID
104770644
Publisher
Springer
Year
1979
Tongue
English
Weight
469 KB
Volume
62
Category
Article
ISSN
0033-3158

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✦ Synopsis

Administration of aminooxyacetic acid (AOAA) and gamma-acetylenic GABA (GAG) resulted in a dose-dependent suppression of aggressive behavior and a concomitant increase in brain GABA. The increase in GABA levels persisted beyond the time when AOAA and GAG exerted an anti-aggressive effect. Brain GABA levels remained significantly elevated over controls for 120 h after a single injection of AOAA and 46 h after a single dose of GAG.

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