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Inhibition of inducible nitric oxide synthase reduces renal ischemia/reperfusion injury

✍ Scribed by Chatterjee, Prabal K.; Patel, Nimesh S.A.; Kvale, Espen O.; Cuzzocrea, Salvatore; Brown, Paul A.J.; Stewart, Keith N.; Mota-Filipe, Helder; Thiemermann, Christoph

Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
517 KB
Volume
61
Category
Article
ISSN
0085-2538

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## Abstract Nitric oxide (NO), originally identified as the mediator of endothelial‐dependent relaxation of vascular smooth muscle, is now known to also have cytotoxic effects under certain conditions. Thus, we have investigated the effects of inhibition of NO synthesis on ischemia/reperfusion inju