Disulfiram-mediated inhibition of NF-κB
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Weiguang Wang; Howard L. McLeod; James Cassidy
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Article
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2003
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John Wiley and Sons
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French
⚖ 732 KB
## Abstract 5‐Fluorouracil (5‐FU) is the major chemotherapeutic component for colorectal cancer (CRC) and other types of solid tumours. Resistance of cancer cells to 5‐FU is considered the major obstacle for successful chemotherapy. NF‐κB is a transcription factor. Cancer cells with high NF‐κB nucl