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Inhibition of in vitro mineralization in osteoblastic cells and in mouse tooth germ by phosphatidylinositol-specific phospholipase C

✍ Scribed by Togari Akifumi; Arakawa Seiichi; Arai Michitsugu; Matsumoto Shosei


Book ID
115783374
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
371 KB
Volume
46
Category
Article
ISSN
0006-2952

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## Abstract Bone marrow stromal cells (BMSCs) can proliferate in vitro and can be transplanted for treating many kinds of diseases. However, BMSCs become senescent with long‐term culture, which inhibits their application. To understand the mechanism underlying the senescence, we investigated the ac