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Inhibition of hypoxia-inducible transcription factor complex with designed epipolythiodiketopiperazine

✍ Scribed by Swati Kushal; Hui Wang; Csaba F. László; Lajos Z. Szábo; Bogdan Z. Olenyuk


Book ID
102762190
Publisher
Wiley (John Wiley & Sons)
Year
2010
Tongue
English
Weight
507 KB
Volume
95
Category
Article
ISSN
0006-3525

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Accumulating studies demonstrate that the expressions of hypoxia-inducible factor 1 (HIF-1), erythropoietin (EPO) and vascular endothelial growth factor (VEGF) depend on cellular oxygen tension, which is involved in the pathological process of tissue hypoxia and/or ischemia. The present study invest